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. 2016 Jun 8;2:16017. doi: 10.1038/npjbcancer.2016.17

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Copyright © 2016 Breast Cancer Research Foundation/Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Five-year estimates of breast-cancer-specific mortality, by Recurrence Score group (prespecified primary analysis). Patients with HR+, HER2-negative, node-negative breast cancer who had Recurrence Score (RS) results <18 (green), 18–30 (yellow), or ⩾31 (red) were included in the primary analysis. Five-year estimates of breast-cancer-specific mortality (BCSM) with 95% CIs (green, yellow, and red shading) were 0.4% (0.3–0.6%) in the RS <18 group, 1.4% (1.1–1.7%) in the RS 18–30 group, and 4.4% (3.4–5.6%) in the RS ⩾31 group. Five-year estimates of BCSM±s.e. are shown to the right of their respective lines. Numbers of patients at risk in each group are shown beneath the graph.