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. 2016 Nov 2;2:16033. doi: 10.1038/npjbcancer.2016.33

Table 2. Multivariate Cox regression analysis of AXL and CD163 for relapse-free survival and overall survival in triple-negative breast cancer (N=203).

Variable HR 95% CI P valuea HR 95% CI P valuea
  Relapse-free survival Overall survival
AXL 2.84 1.45–5.55 2.20E−03 3.09 1.58–6.06 1.00E−03
Age 0.88 0.46–1.69 7.11E−01 1.08 0.57–2.07 8.09E−01
Grade 1.68 0.69–4.11 2.53E−01 2.06 0.84–5.09 1.16E−01
Nodal status 2.53 1.01–6.31 4.72E−02 2.62 1.05–6.55 3.98E−02
Tumor size 1.33 0.69–2.58 3.97E−01 1.17 0.61–2.25 6.30E−01
Tumor stage 1.72 0.81–3.66 1.60E−01 1.67 0.78–3.57 1.88E−01
CD163 1.85 0.96–3.55 6.58E−02 1.63 0.85–3.12 1.40E−01
Age 0.95 0.50–1.80 8.72E−01 1.16 0.61–2.20 6.45E−01
Grade 1.68 0.68–4.13 2.60E−01 1.90 0.77–4.73 1.65E−01
Nodal status 2.90 1.18–7.13 2.02E−02 3.08 1.25–7.59 1.43E−02
Tumor size 1.36 0.70–2.65 3.60E−01 1.19 0.62–2.30 5.99E−01
Tumor stage 1.54 0.74–3.22 2.48E−01 1.41 0.67–2.94 3.66E−01

Abbreviations: CI, confidence interval; HR, hazard ratio.

a

Significant P values are given in bold.

Multivariate analysis adjusted for age (⩾50 vs. <50), histological grade (G3 vs. G1–2), nodal status (1 vs. 0), tumor size (>20 mm vs. ⩽20 mm), and tumor stage (III vs. I–II).