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. Author manuscript; available in PMC: 2017 Jul 18.
Published in final edited form as: Cell Host Microbe. 2013 Mar 13;13(3):336–346. doi: 10.1016/j.chom.2013.01.012

Fig. 2. Influence of the viral 5′ppp group and of RIG-I.

Fig. 2

(A) Cells were CHX treated, infected with LACVdelNSs, PHV or SFV, and assayed as described for Fig. 1. (B) Innate response to VSV or LACVdelNSs by cells treated with CHX and with siRNAs targeting MDA5 or RIG-I. (C) MEFs lacking MDA5 or (D) RIG-I, and the corresponding wt MEFs, were tested for their innate response to tc-VLPs. See also Figs. S8 to S10.