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. Author manuscript; available in PMC: 2017 Jul 18.
Published in final edited form as: Xenobiotica. 2014 Mar 5;44(9):769–774. doi: 10.3109/00498254.2014.895882

Figure 3.

Figure 3

Variations in P450 content in cynomolgus monkeys. The amounts of CYP3A (CYP3A4 + CYP3A5) and CYP2C9/19 immunoquantified in 35 cynomolgus monkey small intestines are shown. The x-axis represents individual jejunum samples, for which animal numbers and sex are also indicated. Of 35 animals analyzed, the CYP3A amount varied the least. In contrast, the CYP2C9/19 amount varied the most among 17 animals with quantifiable CYP2C9/19, but the variations were greatly smaller when the animal with the greatest expression was excluded from the analysis.