Table 1. Characteristics of the population distributed according to bone volume.
| NORMAL BV/TV (N = 38) |
LOW BV/TV (N = 17) |
p-value | |
|---|---|---|---|
| Female | 20 (52.6%) | 08 (47.1%) | 0.45 |
| Age (years) | 54.5 (49–62) | 58 (44–65) | 0.99 |
| Dialysis duration | 37 (27–72) | 76 (36–108) | 0.08 |
| MetS (%) | 28 (73.7%) | 7 (41.2%) | 0.02* |
| Diabetes (%) | 13 (34.2%) | 9 (52.9%) | 0.19 |
| BMI kg/m2 | 27.2 (25–29.6) | 23.7 (20.3–26.7) | <0.01* |
| Body fat (%) | 33.2 (30.4–37.1) | 32.6 (22.6–36.5) | 0.20 |
| Serum creatinine (mg/dL) | 8.7±2.4 | 9.1±2.5 | 0.64 |
| Leptin/BMI | 0.36 (0.29–0.81) | 0.42 (0.23–0.80) | 0.78 |
| Calcium (mg/dL) | 9.3 (8.7–9.8) | 10 (9.5–10.2) | 0.13 |
| Phosphorus (mg/dL) | 5.8 (5.4–6.8) | 5.1 (4.3–5.6) | 0.02* |
| iPTH (pg/dL) | 971 (480–1306) | 506 (320–1437) | 0.62 |
| Glucose (mg/dL) | 85.5 (79–103) | 106 (93–160) | 0.06 |
| Insulin (μUI/mL) | 7.8 (6.3–8.8) | 4.7 (3.3–8.6) | 0.06 |
| HDL (mg/dL) | 38.5 (35–44) | 50 (40–65) | 0.01* |
| c-FGF23 (RU/mL) | 5,771 (3,083–10,320) | 1,480 (488–4,177) | <0.01* |
| Sclerostin (ng/mL) | 1.02 (0.81–1.34) | 1.16 (0.72–1.71) | 0.85 |
| Intact osteocalcin (ng/mL) | 117.5 (47.3–193.5) | 117.7 (74.4–230.6) | 0.46 |
| Phosphate binder Calcium based Sevelamer |
36 (94.7%) 5 (13.1%) 31 (81.5%) |
14 (82.3%) 1 (5.9%) 14 (82.3%) |
0.39 |
| Calcitriol | 20 (52.6%) | 13 (76.5%) | 0.09 |
MetS: metabolic syndrome; BMI: body mass index; iPTH: intact parathyroid hormone; HDL: high-density lipoprotein; c-FGF23: C-terminal fibroblast growth factor 23. Values are expressed as the means±SD, median (min-max) or percentage.
*p<0.05.