Table 2. Characteristics of the population distributed according to the diagnosis of metabolic syndrome.
| Without MetS (n = 20) |
With MetS (n = 35) |
p-value | |
|---|---|---|---|
| Female | 10 (50%) | 18 (51.4%) | 0.91 |
| Age (years) | 48.1±19.1 | 57.4±11.9 | 0.06 |
| Diabetes (%) | 3 (15%) | 19 (54.3%) | <0.01* |
| Dialysis duration (mo) | 114 (6–304) | 36 (8–180) | <0.01* |
| BMI kg/m2 | 23.4±3.2 | 28.7±6.1 | <0.01* |
| Body fat (%) | 28.5 (6.7–36.3) | 36.2 (10.6–46.6) | <0.01* |
| Calcium (mg/dL) | 9.1±1.2 | 9.2±1.1 | 0.63 |
| Phosphorus (mg/dL) | 5.4±1.9 | 6.1±2.1 | 0.14 |
| iPTH (pg/dL) | 1,096 (130–2,989) | 720 (43–1,643) | 0.76 |
| AP (U/L) | 196 (53–734) | 147 (73–978) | 0.23 |
| Albumin (g/dL) | 3.8±0.5 | 3.7±0.4 | 0.82 |
| CRP (mg/dL) | 0.8 (0.5–23.3) | 0.6 (0.5–21) | 0.58 |
| Glucose (mg/dL) | 86 (68–155) | 103 (72–356) | 0.04* |
| Cholesterol (mg/dL) | 126.7±34.7 | 143.5±29.6 | 0.06 |
| LDL (mg/dL) | 57.4±28.7 | 66.1±25.9 | 0.16 |
| HDL (mg/dL) | 42 (22–88) | 40.5 (24–90) | 0.13 |
| Triglyceride (mg/dL) | 92.1 (38–406.9) | 155 (66–385) | <0.01* |
| Ferritin (ng/mL) | 713.4 (194–6,274) | 664.6 (60.2–4,420) | 0.86 |
| 25-OH-VitD (ng/mL) | 30.9 ±10.8 | 28.8±12.1 | 0.40 |
| HOMA-IR | 1.0 (0.53–3.3) | 2.3 (0.3–24.8) | <0.01* |
| Insulin (μIU/mL) | 5.5 (2.7–16.3) | 8.4 (2.0–65.4) | <0.01* |
| Magnesium (mg/dL) | 2.2 (1.4–2.9) | 2.1 (1.6–2.9) | 0.58 |
| TSH (μIU/mL) | 2.4 (0.2–9.1) | 2.01 (0.59–16.97) | 0.59 |
| T4 (ng/mL) | 1.1 (0.7–2.3) | 0.97 (0.64–1.73) | 0.33 |
| Leptin (ng/mL) | 6.5 (1.0–20.6) | 17.05 (1–475.2) | <0.01* |
| Leptin/BMI | 0.36 (0.29–0.81) | 0.42 (0.23–0.80) | 0.78 |
| c-FGF23 (RU/mL) | 5,315 (480–13,130) | 3,552 (382–77,055) | 0.06 |
| Sclerostin (ng/mL) | 0.9 (0.3–2.8) | 1.75 (0.2–3.3) | 0.30 |
| Osteocalcin (ng/mL) | 173.7 (12.3–556.2) | 107.6 (9.3–414.1) | 0.26 |
| FSH (mIU/mL) | 10.1 (3.1–150) | 39.96 (0.24–150) | 0.78 |
| Estrogen (pg/mL) | 24.5 (10–226) | 26.5 (13–449) | 0.32 |
| BV/TV (%) | 17.3±6.93 | 19.8±7.0 | 0.16 |
| BFR/BS (μm3/μm2/day) | 0.044 (0.0003–1.83) | 0.049 (0.003–2.57) | 0.66 |
| MLT (days) | 72,39 (5.99–100) | 55.57 (8.41–100) | 0.47 |
MetS: metabolic syndrome; BMI: body mass index; iPTH: intact parathyroid hormone; AP: alkaline phosphatase; CRP: C-reactive protein; LDL: low-density lipoprotein; HDL: high-density lipoprotein; 25-OH-VitD: 25 hydroxyvitamin d; HOMA-IR: homeostatic model assessment-insulin resistance; TSH: thyroid-stimulating hormone; T4: free tetra-iodo-thyroxine; c-FGF23: C-terminal fibroblast growth factor 23; FSH: follicle-stimulating hormone. Values are expressed as the means±SD, median (min-max) or percentage.
*p<0.05.