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. 2017 Jul 18;12(7):e0181015. doi: 10.1371/journal.pone.0181015

Fig 3. Analysis of gene-expression patterns of INF-signature related genes and T-cell subset related cytokines.

Fig 3

A, After induction of PIL in contrast to the mir155-deficient group PIL-/- and controls (CO+/+), INF-related genes were upregulated in the lupus wild type group PIL+/+. B, Cytokines related to the T-cell subsets (Th1, Th2, Th17) were significantly upregulated in PIL+/+, but not in PIL-/- and CO+/+. Results are representative of 2 independent experiments. PIL were induced with pristane, CO with PBS; +/+ stands for wild type, -/- for miR155-deficient knockouts; bars show mean with SD. * = P < 0.05, by Mann-Whitney test.