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. 2017 Jul 18;12(7):e0181387. doi: 10.1371/journal.pone.0181387

Fig 4.

Fig 4

Whole body (A), appendicular (B), and leg (C) lean mass over the course of the study. Boxes (SUPP: grey; CON: white) represent interquartile (25th to 75th percentile) ranges, with the horizontal lines indicating the medians. Whiskers represent the maximal and minimal values, and the crosses indicate the means. Data was analyzed using a linear mixed model with group (SUPP or CON), time (prior to study entry, and weeks 6 and 19), and the group-by-time interaction as fixed factors; subject as a random factor; and baseline values as covariates. We observed significant group-by-time interactions for whole body (P < 0.01), appendicular (P = 0.021), and leg lean mass (P = 0.015). Dissimilar letters denote changes over time within a given treatment group (SUPP or CON). SUPP, supplement group (n = 25); CON, control group (n = 24).