Table 1. Crawling and swimming behaviors and dbl-1 and wrt-4 gene expression in dbl-1, sma-4, unc-8, dop-4, and unc-68 mutants.
Strains |
Moving behavior |
Gene expression (liquid versus agar) |
||
---|---|---|---|---|
Crawling (Hz) | Swimming (Hz) | dbl-1 (fold change) | wrt-4 (fold change) | |
N2 | 0.65±0.18 | 1.66±0.18 | 2.22±0.08 | 9.24±1.40 |
LT121 dbl-1 (wk70) | 0.41±0.10** | 1.40±0.25* | 1.42±0.02 | 0.36±0.05 |
DR1369 sma-4 (e729) | 0.46±0.11** | 1.57±0.15 | 1.36±0.07 | 0.47±0.03 |
CB15 unc-8 (e15) | 0.23±0.07*** | 0.27±0.16*** | 1.11±0.01 | 0.60±0.06 |
FG58 dop-4 (tm1392) | 0.54±0.17 | 1.48±0.21* | 0.89±0.01 | 0.66±0.03 |
TR2170 unc-68 (r1161) | 0.22±0.07*** | 0.46±0.15*** | 1.48±0.04 | 1.56±0.11 |
Dorsal and ventral (DV) head bending cycle was counted for 30 s under stereo microscopy as contraction rate of swimming or crawling, just after tapping each culture plate. (n=10 worms per condition; *P≤0.05, **P≤0.01, ***P≤0.001).