Table I.
Examples for RBC storage times currently approved and applied depending on the additive solution
Additive solution* and shelf life (days)
|
Country | |
---|---|---|
Approved | Applied in clinical service | |
49 days | 49 days | Germany and Switzerland1 |
49 days | 42 days | Germany1 |
42 days | 42 days | Canada, China, Malaysia, and USA;2 Thailand;2,3 Argentina, Australia, Austria, Brazil, France, Germany, India, Italy, Saudi-Arabia, Switzerland, Spain, and Tunisia3 |
42 days | 35 days | China;2,3,4 Netherlands and United Kingdom (uniform for the countries);3 Germany (large blood services for >20 years)3 |
42 days | 21 days | Japan4 |
35 days | 35 days | Brazil, China, Ethiopia, India, Malaysia, Oman, Pakistan, and Tunisia5 |
21 days | 21 days | China and Saudi-Arabia (few blood services)6 |
1PAGGS-M (phosphate-adenine-glucose-guanosin-saline-mannitol, 285 mOsm/l isotonic): approved for a shelf life of 49 days; 2AS-3 (saline-adenine-glucose-citrate-phosphate): 42 days; 3SAGM (saline-adenine-glucose-mannitol, 376 mOsm/L hypertonic): 42 days; 4MAP (mannitol-adenine-phosphate): 42 days;;; 5CPDA-1 ( citrate-phosphate-dextrose-adenine): 35 days; 6CPD (citrate-phosphate-dextrose): 21 days.