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Toxicity in Metformin in HNSCC Clinical Trial as per NCI CTCAEv4.0 Scoring.
| Metformin‐Related Toxicity | ||
|---|---|---|
| Toxicity | Grade | n |
| Diarrhea | 1 | 10 |
| Nausea | 1 | 2 |
| Fatigue | 1 | 1 |
| Weakness | 1 | 1 |
| Dizziness | 1 | 1 |
| Increased ALT | 1 | 1 |
| Diarrhea | 2 | 1 |
| Nausea | 2 | 1 |
| Hemorrhoids | 2 | 1 |
ALT = alanine aminotransferase; CTCAE = Common Terminology Criteria for Adverse Events; HNSCC = head and neck squamous cell carcinoma; NCI = National Cancer Institute.
