Figure 2. Effects of ketoprofen on lactic acid-induced impairment of visual attention performance.
A. Ketoprofen reduced the effect of 1.8% lactic acid on median cue duration in a dose-dependent manner [F(4,67)=20.1, p<0.0001]. Saline and ketoprofen at any dose had no effect on median cue duration in the absence of lactic acid administration. (BSL: Baseline, SAL: Saline) (*:p<0.05 compared to BSL, #: p<0.05 compared to SAL/SAL, $: p<0.05 compared to SAL/1.8% lactic acid, &: p<0.05 compared to 0.03Ket/1.8% lactic acid). Mean and S.D. are shown, N=10–15/group. B. Representative visual cue duration titration curves are shown. Each curve represents an individual session of 100 trials on a given day and treatment.