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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Anesthesiology. 2017 Aug;127(2):372–381. doi: 10.1097/ALN.0000000000001702

Figure 4. Effects of scopolamine on visual attention performance and lack of reversal by ketoprofen and morphine.

Figure 4

A. Scopolamine disrupted performance in the 5CTV as evidenced by a dose dependent increase in the median cue duration [F(4,66)=22.6, p<0.0001]. Saline or 0.03 mg/kg of scopolamine did not produce a signficant increase in median cue duration relative to baseline values (BSL: Baseline, SAL: Saline) (*:p<0.05 compared to BSL, #: p<0.05 compared to SAL). Mean and S.D. are shown, N=13–15/group B. Representative visual cue duration titration curves are shown. Each curve represents an individual session of 100 trials on a given day and treatment. C. Neither 0.3 mg/kg of ketoprofen nor 3 mg/kg of morphine altered the effect of 0.1 mg/kg of scopolamine on the median cue duration (p>0.05). Mean and S.D. are shown, N=11–13/group. D. Representative visual cue duration titration curves are shown for scopolamine and either ketoprofen or morphine.