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. Author manuscript; available in PMC: 2018 Mar 28.
Published in final edited form as: ACS Nano. 2016 Sep 28;10(10):9243–9258. doi: 10.1021/acsnano.6b02776

Figure 8.

Figure 8

Binding affinity and uptake rate of LCP NPs (S/L, ±AA) in UMUC3 and activated fibroblasts. (A) Binding curve of AA L-LCP NPs for activated NIH3T3 and sorted GFP-fibroblasts from the stroma-rich bladder tumor models. (B) Binding affinity of LCP NPs (S/L, ±AA) in UMUC3 and activated NIH3T3. The data points were fitted to Michaels–Menten curve, KD, and Vmax were calculated and shown in the chart. Time-dependent uptake of 1 nM LCP NPs (S/L) with or without AA in activated NIH3T3 and UMUC3 is shown in (C) and (D), respectively (n = 3).