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. 2017 Jul 19;8:339. doi: 10.3389/fneur.2017.00339

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Copyright © 2017 Hu, Du, Xu, Yang, Zeng, Dai, Liu, Lu and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparative results of voxel-wise one-way repeated measures analysis of variance (ANOVA) (P < 0.001) and post hoc testing (P < 0.01) for motion-related activation and resting-state functional connectivity (RSFC) across the three stages of progression. (A) Motion-related activation results. Compared with the acute stage, motion-related activation was reduced in the ipsilesional sensorimotor cortex during the subacute stage. Compared with the acute and subacute stages, motion-related activation increased significantly during the early chronic stage. (B) RSFC results from the ipsilesional sensorimotor cortex. Compared with the acute stage, the RSFC of the ipsilesional sensorimotor cortex was reduced during the subacute stage. Compared with the acute and subacute stages, the FC of the ipsilesional sensorimotor cortex increased significantly during the early chronic stage. Ipsi, the ipsilesional hemisphere; Contra, the contralesional hemisphere.