Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jul 18;7:5708. doi: 10.1038/s41598-017-06137-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Study design and Selection of plasma miRNA candidates. (a) Study design to find novel candidate miRNAs that decreased in patient plasma as a therapeutic target for PCa. (b) Using a miRNA array-based approach, we found decreased plasma miRNAs with tumor suppressor functions by comparing the plasma levels of each miRNA between PCa patients and healthy volunteers. (c) Small-scale analysis of the plasma levels of six miRNAs in PCa patients and healthy volunteers by qRT-PCR. We investigated the plasma levels of the six selected miRNAs in 10 PCa patients and 10 healthy volunteers by qRT-PCR. The miRNA array-based approach showed that all six candidate miRNAs tended to be lower in the plasma of PCa patients than in that of healthy volunteers, and the change in the expression of miR-107 (P = 0.027) was found to be the most significant.