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. 2017 Jul 18;7:5744. doi: 10.1038/s41598-017-06057-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Results of cortical volume comparisons among Internet gaming disorder (IGD), alcohol use disorder (AUD), and healthy controls (HCs). (a) Areas of significant larger gray matter volume in IGD than HCs. ^†The cluster size of the right hippocampus/amygdala did not reach the level of significace (883 voxels; minimum cluster size for significance = 953 voxels). (b) Areas of significant smaller gray matter volume in AUD than HCs. (c) Average gray matter volumes of the significant clusters for each group. Error bars denote standard error of the mean. *p < 0.05; **p < 0.01; ***p < 0.005; ****p ≤ 0.001; HC, healthy control; AUD, alcohol use disorder; IGD, Internet gaming disorder; L, left; R, right; L_Hipp, left hippocampus; R_Hipp, right hippocampus; R_PCN, right precuneus; L_Cbll, left cerebellum; R_Cbll, right cerebellum.