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. 2017 Jul 18;7:5718. doi: 10.1038/s41598-017-06408-4

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Analysis of behavioral parameters for the data obtained during the basal stage. The numbers of rats in each group were as shown in Fig. 1c. Values are expressed as mean + standard error of the mean. (a) Reward latency. **p < 0.01; significantly higher in the seeking-paired than in the averse-paired group. ***p < 0.001; significantly higher in the seeking-isolated than in the averse-isolated group. ^† p < 0.05; significant differences between the seeking-paired and seeking-isolated groups. (b) Premature response. *p < 0.05; significantly higher in the seeking-paired compared to the averse-paired group. (c) Perseverative screen touch. **p < 0.01; significantly higher in the seeking-paired compared to the averse-paired group. **p < 0.01; significantly higher in the seeking-isolated compared to the averse-isolated group. (d) Feed-tray entry. ^† p < 0.05; significant differences between the seeking-paired and seeking-isolated groups. (e) Omission. There was no significant difference between groups.