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. 2017 Jul 19;8:327. doi: 10.3389/fneur.2017.00327

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Copyright © 2017 Valdés Hernández, González-Castro, Chappell, Sakka, Makin, Armitage, Nailon and Wardlaw.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Measures of homogeneity (A) and variability (B) of the texture in the index stroke lesions between patients with lacunar and cortical ischemic stroke. The energy in panel (A) has been multiplied by 15 to give a similar range to the gray level co-occurrence matrix (GLCM) correlation and homogeneity, for visualization purposes (*p < 0.05; **p < 0.001). Median outputs from the six textural characteristics (i.e., three representing homogeneity and three representing variability in texture) are displayed grouped by cortical vs. lacunar, showing that texture in the index stroke lesion was more homogeneous in patients with cortical stroke rather than in those who had a lacunar stroke and that, consequently, heterogeneity was higher in lacunar than in cortical stroke lesions.