Figure 2.

The moderational influences of BDNF genotype and self-efficacy beliefs on the relations between loneliness and depression. At 1 SD below the mean of self-efficacy (A), depressive scores were more pronounced with increased loneliness experiences, particularly among Met carriers. At mean levels of self-efficacy (B), depressive symptoms were similar, though slightly elevated among Val/Val individuals across loneliness perceptions. At 1 SD above the mean of self-efficacy (C), Met carriers exhibited consistent depression scores across levels of social isolation, whereas those with homozygous Val alleles reported elevated depressive symptoms with increased loneliness perceptions.