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. 2017 Jul 19;11:213. doi: 10.3389/fncel.2017.00213

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Copyright © 2017 Xiong, Liu, Deng, Liu, Dan, Zhang, Zou, Xia and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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HSC transplantation promoted oligogenesis. Compared with the sham group, the number of APC positive cells was largely decreased in the injured center, rostral and caudal spinal cord near the injured site post SCT (A–D). Comparatively, the number of oligodendrocytes was effectively increased at 24 weeks post-SCT (E–H). Quantitative histogram showed that the number of oligodendrocytes in HSC group was higher than that of the SCT one (I–L). (A,E,I) Scar center; (B,F,J) Posterior Funiculus of rostral scar; (C,G,K) gray matter of rostral scar; (D,H,I) Dorsal horn of caudal scar. Data are presented as the mean ± SD (n = 7). Student’s t test was used to analyze the data. Data in the sham group were not shown. *P < 0.05 vs. SCT. Bar = 50 μm.