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Summary of drugs targeting the cytoskeleton and their mode of action.
| Target | Drugs | Used Concentration (μM) | Mode of Action |
|---|---|---|---|
| Microfilaments | Cytochalsin D | 2.5 | Binds to filamentous actin and disrupts polymerization32 |
| Jasplakinolide | 0.7 | Binds to filamentous actin and stabilizes33 | |
| Microtubules | Nocodazole | 18.75 | Binds to β-tubulin and prevents interchain bonds34 |
| Paclitaxel | 31.5 | Binds to assembled microtubules and enhances the formation of highly stable microtubules35 |
