Figure 3.
Protective immunity after lethal challenge with homologous virus of mice immunized during pregnancy. Immunized groups were challenged with mouse adapted A/Brisbane/59/07 (H1N1) virus 4 weeks after immunization. (A and C) Body weight changes and (B and D) survival rates after challenge with 5xLD50 of virus were monitored for 14 days. Values are expressed as mean +/− SEM. (n = 5–14). Groups and animal numbers are as described in Fig. 2; *p < 0.05; **p < 0.01.