Table 1.
IsoDGR-containing peptides identified by LC-MS/MS analysis of human carotid atherosclerotic plaques.
| Accession | Gene | Protein | Most abundant modified peptide | Modified site | N#GR | NGR | Total | % N#GR |
|---|---|---|---|---|---|---|---|---|
| P01023 | A2M | Alpha-2-macroglobulin | K.EQAPHCICAN#GR.Q | 851 | 22 | 7 | 29 | 75.9 |
| C9JF17 | APOD | Apolipoprotein D | R.WYEIEKIPTTFEN#GR.C | 86 | 59 | 9 | 68 | 86.8 |
| P51452 | DUSP3 | Dual specificity protein phosphatase 3 | R.AADFIDQALAQKN#GR.V | 117 | 6 | 3 | 9 | 66.7 |
| A0A0C4DFX3 | EMILIN1 | EMILIN-1 | R.AVETAFN#GR.Q | 219 | 10 | 0 | 10 | 100.0 |
| FA9 | F9 | Coagulation factor IX | K.NCELDVTCNIKN#GR.C | 138 | 6 | 1 | 7 | 85.7 |
| P35555 | FBN1 | Fibrillin-1 | R.DIDECLQN#GR.I | 537 | 65 | 10 | 75 | 86.7 |
| P35555 | FBN1 | Fibrillin-1 | R.DIDECLQN#GRICN#N#GR.C | 543 | 9 | 25 | 34 | 26.5 |
| P35555 | FBN1 | Fibrillin-1 | R.YCKDINECETPGICMN#GR.C | 625 | 44 | 68 | 112 | 39.3 |
| P35555 | FBN1 | Fibrillin-1 | R.RPDGEGCVDENECQTKPGICEN#GR.C | 2304 | 11 | 42 | 53 | 20.8 |
| C9JC84 | FGG | Fibrinogen gamma chain | R.VELEDWN#GR.T | 288 | 73 | 156 | 229 | 31.9 |
| P02751 | FN1 | Fibronectin | R.GNLLQCICTGN#GRGEWK.C | 263 | 54 | 43 | 97 | 55.7 |
| P02751 | FN1 | Fibronectin | K.QMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPFTYN#GR.T | 367 | 5 | 76 | 81 | 6.2 |
| P02751 | FN1 | Fibronectin | R.CTCVGN#GRGEWTCIAYSQLR.D | 501 | 9 | 16 | 25 | 36.0 |
| P02751 | FN1 | Fibronectin | R.NSITLTNLTPGTEYVVSIVALN#GR.E | 1432 | 29 | 91 | 120 | 24.2 |
| P10915 | HAPLN1 | Hyaluronan and proteoglycan link protein 1 | K.SRYDVFCFTSN#FN#GR.F | 258 | 28 | 29 | 57 | 49.1 |
| A0A0G2JIW1 | HSPA1B | Heat shock 70 kDa protein 1B | K.LLQDFFN#GRDLNK.S | 356 | 11 | 11 | 22 | 50.0 |
| P11021 | HSPA5 | 78 kDa glucose-regulated protein | K.N#GRVEIIANDQGNR.I | 47 | 3 | 7 | 10 | 30.0 |
| P11047 | LAMC1 | Laminin subunit gamma-1 | R.ATAESASECLPCDCN#GR.S | 345 | 6 | 30 | 36 | 16.7 |
| Q08397 | LOXL1 | Lysyl oxidase homolog 1 | R.LSVGSVYRPNQN#GRGLPDLVPDPN#YVQASTYVQR.A | 365 | 12 | 0 | 12 | 100.0 |
| Q15149 | PLEC | Plectin | K.TLPN#GRDALDGPAAEAEPEHSFDGLRR.K | 2765 | 30 | 2 | 32 | 93.8 |
| P08567 | PLEK | Pleckstrin | R.GCVVTSVESNSN#GR.K | 305 | 10 | 3 | 13 | 76.9 |
| PLMN | PLG | Plasminogen | R.YEFLN#GR.V | 736 | 44 | 2 | 46 | 95.7 |
| K7EKI8 | PPL | Periplakin | R.SLLDLEN#GR.R | 814 | 4 | 0 | 4 | 100.0 |
| H7C2N1 | PTMA | Prothymosin alpha (Fragment) | K.EVVEEAEN#GR.D | 67 | 20 | 26 | 46 | 43.5 |
| Q96B97 | SH3KBP1 | SH3 domain-containing kinase-binding protein 1 | R.KEDGGWWEGQIN#GR.R | 42 | 2 | 1 | 3 | 66.7 |
| H0Y7S5 | SHANK2 | SH3 and multiple ankyrin repeat domains protein 2 | -.FM#N#VPGGGAAAVMMTGYNN#GR.C | 19 | 2 | 0 | 2 | 100.0 |
| A0A0C4DG40 | SYNE1 | Nesprin-1 | R.DLQ#DRLSQMN#GRWDR.V | 8480 | 1 | 0 | 1 | 100.0 |
| A0JNU9 | TBC1D1 | TBC1 domain family member 1 | R.KQ#N#LDLLEQLQ#VAN#GR.I | 369 | 1 | 0 | 1 | 100.0 |
| J3QSU6 | TNC | Tenascin | K.N#GRENFYQNWK.A | 1849 | 3 | 3 | 6 | 50.0 |
| J3QSU6 | TNC | Tenascin | K.VEGYSGTAGDSMAYHN#GR.S | 1936 | 14 | 62 | 76 | 18.4 |
| O76076 | WISP2 | WNT1-inducible-signaling pathway protein 2 | R.GALCLLAEDDSSCEVN#GR.L | 103 | 15 | 82 | 97 | 15.5 |