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. 2017 Apr 3;91(8):2723–2743. doi: 10.1007/s00204-017-1962-5

Table 2.

Proposed equivalences between the UN-GHS and IARC classification schemes

Category 1A Category 1B Category 2 No classification
UN-GHS and CLP Substances known to have carcinogenic potential for humans
Largely based on human evidence
Substances presumed to have carcinogenic potential for humans
Largely based on animal evidence
Substances suspected to have carcinogenic potential for humans
Evidence obtained from human and/or animal studies but not sufficiently convincing to place the
Substance in Category 1A or 1B
No sufficient evidence for classifying the substance as carcinogenic
Group 1 Group 2A Group 2B Group 3 Group 4
IARC The agent is a carcinogen for humans. This category is only used when sufficient indications of carcinogenicity for humans are available The agent is probably carcinogenic for humans. The classification of an agent in this category is recommended if there is no formal evidence of carcinogenicity in humans, but corroborating indicators of its carcinogenicity for humans and sufficient evidence of carcinogenicity in experimental animals The agent is possibly carcinogenic for humans. There is limited evidence of carcinogenicity in humans and evidence for animals, or insufficient evidence for human beings but sufficient evidence of carcinogenicity in experimental animals Agent not classifiable as to its carcinogenicity to humans. (Insufficient evidence for human beings and insufficient or limited for animals) Agent probably not carcinogenic for humans. (Evidence suggesting lack of carcinogenicity in humans and in experimental animals)