. 2005 Feb 12;5:14. doi: 10.1186/1471-2148-5-14

Table 3.

Synonymous (d_S) and nonsynonymous (d_N) substitution rate estimates for all relaxin-like genes. Substitution rates were estimated using the Yang and Neilsen, 2000 method as implemented in yn00 in the PAML suite. Estimations were made using pairwise alignments of the nucleotide sequences of the B and A domains of human and chimpanzee or human and mouse genes. A d_N/d_Sof 99 represents infinity and indicates that all substitutions detected are nonsynonymous, while na indicates that a d_N/d_Smeasurement is not possible as the sequences being compared are identical, or have only synonymous substitutions.

	human- chimpanzee			human-mouse

	d_N	d_S	d_N/d_S	d_N	d_S	d_N/d_S
*RLN1*	0.055	0.039	1.4			_^a
*RLN2*	0.017	0.023	0.7	0.56	1.06	0.5
*RLN3*	0	0	na	0.04	1.83	0.02
*INSL3*	0	0	na	0.17	1.31	0.1
*INSL4*	0	0.027	na			_^a
*INSL5*	0	0.023	na	0.16	1.24	0.1
*INSL6*	0.006	0	99	0.33	0.65	0.5
*INS*	0	0.13	na	0.033	1.44	0.02

^aThese genes are not present in the mouse.