Table 1.

Characteristics of Enrolled Patients

	TBI				CONTROL
Characteristics	Total	University of Florida	Regional Orlando Medical Center	Washington University	Normal Controls	Trauma Controls
	N=96	N=26	N=52	N=18	N=176	N=23
Mean age (yrs±SD)	39 (±15)	36 (±15)	39 (±15)	46 (±15)	37 (±14)	44 (±17)
Range	(18–89)	(18–61)	(19–70)	(23–89)	(18–65)	(19–83)
Gender (%)
male/female	64/36	62/39	64/36	67/33	53/47	70/30
GCS Score in ED (%)
GCS 9–12	10 (10)	5 (19)	3 (6)	2 (11)	0 (0)	0 (0)
GCS 13–15	86 (90)	21 (81)	49 (94)	16 (89)	176 (100)	23 (100)
Mechanism of Injury
Motor Vehicle Crash	43 (45)	16 (61)	25 (47)	2 (11)	0 (0)	16 (70)
Fall	14 (15)	2 (8)	6 (13)	6 (33)	0 (0)	2 (9)
Motorcycle	14 (15)	2 (8)	11 (21)	1 (6)	0 (0)	0 (0)
Pedestrian Struck	7 (7)	3 (11)	3 (6)	1 (6)	0 (0)	1 (4)
Bicycle	6 (6)	0 (0)	4 (7)	2 (11)	0 (0)	0 (0)
Hit with blunt object	5 (5)	1 (4)	1 (2)	3 (17)	0 (0)	0 (0)
Assault	4 (4)	0 (0)	2 (4)	2 (11)	0 (0)	0 (0)
Sports/Other	3 (3)	2 (8)	0 (0)	1 (6)	0 (0)	4 (17)
Loss of Consciousness (%)
Yes	70 (73)	18 (69)	42 (81)	10 (56)	0 (0)	0 (0)
No	22 (23)	6 (23)	10 (19)	6 (33)	176 (100)	9 (100)
Unknown	4 (4)	2 (8)	0 (0)	2 (11)	0 (0)	0 (0)
Amnesia (%)	37 (39)	10 (38)	22 (42)	5 (28)	0 (0)	0 (0)
Admitted to Hospital (%)	58 (60)	24 (92)	26 (50)	8 (44)	0 (0)	10 (43)
Intoxicated (Alcohol or Drugs)	13 (14)	7 (27)	4 (2)	2 (11)	–	1 (4)
Neurosurgical Intervention	14 (15)	5 (19)	8 (15)	1 (6)	–	0 (0)
Traumatic Intracranial Lesions on CT Scan of Head	28 (29)	11 (42)	11 (21)	6 (33)	–	0 (0)
Lesion Types*
Epidural hematoma	2 (7)	1 (9)	1 (9)	0 (0)		0 (0)
Subdural hematoma	5 (18)	0 (0)	1 (9)	4 (66)		0 (0)
Subarachnoid hemorrhage	6 (21)	3 (27)	2 (18)	1 (17)	–	0 (0)
Contusion	3 (11)	3 (27)	0 (0)	0 (0)		0 (0)
Intracerebral hemorrhage	1 (4)	0 (0)	1 (9)	0 (0)		0 (0)
Pneumocephalus	2 (7)	0 (0)	2 (18)	0 (0)		0 (0)
Diffuse Axonal Lesions	0 (0)	0 (0)	0 (0)	0 (0)		0 (0)
Combination of lesions§	9 (32)	4 (37)	4 (37)	1 (17)		0 (0)

^*Isolated lesions

^§Includes any combination of the above lesions