Table 2. Comparison between clinical data of patients at baseline and after three months treatment with allopurinol .

Index	At baseline	After treatment	P
EF, %, mean (SD)	21.50 (6.8)	22.16 (7.6)	0.35
NYHA FC, N (%)
FC I	14 (46.7)	28 (93.3)	<0.001
FC II	10 (33.3)	2 (6.7)
FC III	6 (20)	0 (0)
Orthopnea, N (%)	14 (46.7)	7 (23.3)	0.016
PND, N (%)	8 (26.6)	6 (20)	0.5
Swelling, N (%)	9 (30)	7 (23.3)	0.5
Fatigue, N (%)	12 (40)	6 (20)	0.03
Anorexia, N (%)	9 (30)	4 (13.3)	0.06
Low back pain, N (%)	9 (30)	8 (26.6)	1
Leg pain, N (%)	9 (30)	4 (13.3)	0.06
Muscle cramp, N (%)	9 (30)	3 (10)	0.03
Nausea and vomiting, N (%)	3 (10)	2 (6.7)	1
Abdominal pain, N (%)	1 (3.3)	1 (3.3)	1
Skin rash, N (%)	1 (3.3)	2 (6.7)	1

Abbreviations: EF, ejection fraction; NYHA FC, New York Heart Association Functional Class; PND, paroxysmal nocturnal dyspnea.