Table 3. Changes in laboratory test results of patients after three months of treatment with allopurinol .

Index	At baseline	After treatment	P value
BUN, mg/dL, mean (SD)	21.2 (6.6)	22.6 (12.0)	0.33
Cr, mg/dL, mean (SD)	0.9 (0.2)	0.9 (0.2)	0.84
Hb, g/dl, mean (SD)	13.3 (1.9)	13.2 (1.8)	0.82
Mg, mg/dL, mean (SD)	1.9 (0.1)	2.1 (0.1)	0.07
K, mg/dL, mean (SD)	4.2 (0.4)	4.1 (0.5)	0.29
Uric acid, mg/dL, mean (SD)	5.9 (1.3)	3.1 (0.9)	<0.001
AST, units/L, mean (SD)	20.9 (6.3)	20.8 (6.7)	0.81
ALT, units/L, median (IQR)	21 (17-24)	20 (17-24)	0.51
ALP, units/L, mean (SD)	219.2 (68.2)	226.1 (68.8)	0.70
Total bilirubin, mg/dL, median (IQR)	0.9 (0.5-1.1)	0.9 (0.5-1.1)	0.59
Direct bilirubin, mg/dL, mean (SD)	0.3 (0.1)	0.2 (0.1)	0.14
ESR, mm/h, mean (SD)	24 (17.6)	16 (12.3)	<0.001
hs-CRP, mg/L, median (IQR)	4.8 (4.7-5.2)	5 (4.1-5.4)	0.71
NT-pro BNP, ng/mL, median (IQR)	782 (522.7-1000)	630 (405-895.7)	<0.001

Abbreviations; BUN, blood urea nitrogen; Cr, creatinine; Hb, hemoglobin; Mg, magnesium; K, potassium; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; ESR: erythrocyte sedimentation rate; hs-CRP: high sensitivity C reactive protein; NT-pro BNP, N terminal pro brain type natriuretic peptide; SD, standard deviation; IQR, interquartile range.