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. 2017 Jul 19;8:1370. doi: 10.3389/fmicb.2017.01370

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Copyright © 2017 Machuca, Recacha, Briales, Díaz-de-Alba, Blazquez, Pascual and Rodríguez-Martínez.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Overlap between differently expressed genes (greater than or equal to 30-fold, p-value < 0.05) on exposure to ciprofloxacin (1 μg/mL) between low-level quinolone resistant (LLQR) cells compared to the wild-type cells in the same conditions. Venn diagram shows the overlap. The numbers indicated on the diagram refer to the number of genes with significantly altered expression levels in one or both conditions. LLQR phenotypes: EC14 means E. coli ATCC 25922 pBK-QnrS1; EC19 means E. coli ATCC 25922 ΔmarR pBK-QnrS1; and EC24 means E. coli ATCC 25922 S83L pBK-QnrS1.