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. 2017 Jul 19;8:1370. doi: 10.3389/fmicb.2017.01370

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Copyright © 2017 Machuca, Recacha, Briales, Díaz-de-Alba, Blazquez, Pascual and Rodríguez-Martínez.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Impact on ROS response of low-level quinolone-resistant (LLQR) cells exposed to 1 μg/mL of ciprofloxacin compared to wild-type cells in the same conditions. LLQR phenotypes: EC14 means E. coli ATCC 25922 pBK-QnrS1; EC19 means E. coli ATCC 25922 ΔmarR pBK-QnrS1; and EC24 means E. coli ATCC 25922 S83L pBK-QnrS1. All indicated genes show a significantly different pattern of expression between LLQR strains and wild-type E. coli (p-value < 0.05). Standard deviations were within 10% of the means.