Table 1.
Clinical features of the high‐MELD score recipients in adult living donor liver transplantation
| Total (n = 327) | Non‐ACLF (n = 137) | ACLF (n = 190) | p | |
|---|---|---|---|---|
| Age (years) | 46.7 ± 8.8 | 45.8 ± 8.6 | 47.2 ± 8.9 | 0.173 |
| Male | 212 (64.8%) | 87 (63.5%) | 125 (65.8%) | 0.440 |
| Etiology, HBV | 260 (79.5%) | 110 (80.3%) | 150 (78.9%) | 0.773 |
| Alcoholic | 28 (8.6%) | 11 (8.0%) | 17 (8.9%) | |
| HCV | 8 (2.4%) | 1 (0.7%) | 7 (3.7%) | |
| AIH | 6 (1.8%) | 3 (2.2%) | 3 (1.6%) | |
| Wilson's | 6 (1.8%) | 3 (2.2%) | 3 (1.6%) | |
| SBC | 5 ((1.5%) | 3 (2.2%) | 2 (1.1%) | |
| PBC | 4 (1.2%) | 2 (1.5%) | 2 (1.1%) | |
| Others | 10 (3.1%) | 4 (2.9%) | 4 (3.2%) | |
| HCC | 35 (10.7%) | 11 (8.0%) | 24 (12.6%) | 0.125 |
| MELD score | 36.4 ± 6.2 | 33.7 ± 3.8 | 38.4 ± 6.9 | <0.001 |
| Total bilirubin | 30.5 ± 13.5 mg/dL | 31.0 ± 10.4 mg/dL | 30.1 ± 15.3 mg/dL | 0.529 |
| Creatinine | 2.0 ± 1.8 mg/dL | 1.1 ± 0.4 mg/dL | 2.6 ± 2.2 mg/dL | <0.001 |
| INR | 3.2 ± 1.5 | 3.3 ± 1.2 | 3.1 ± 1.7 | 0.226 |
| HEP grade 3, 4 | 107 (32.7%) | 0 (0%) | 107 (56.6%) | <0.001 |
| HRS | 130 (39.8%) | 0 (0%) | 130 (68.8%) | <0.001 |
| Hemodialysis | 81 (24.8%) | 0 (0%) | 81 (42.9%) | <0.001 |
| Ventilator | 68 (20.8%) | 0 (0%) | 68 (36.0%) | <0.001 |
| Vasopressor | 37 (11.3%) | 0 (0%) | 37 (19.5%) | <0.001 |
| ICU‐bound | 130 (39.8%) | 3 (2.2%) | 127 (67.2%) | <0.001 |
| Graft type, RL | 233 (71.3%) | 91 (65.9%) | 142 (75.1%) | 0.028 |
| LL | 33 (10.1%) | 21 (15.2%) | 12 (6.3%) | |
| Dual | 61 (18.7%) | 26 (18.8%) | 35 (18.5%) | |
| Graft weight | 691 ± 142 g | 671 ± 148 g | 705 ± 135 g | 0.054 |
| GRWR | 1.0 ± 0.21% | 1.0 ± 0.20% | 1.0 ± 0.23% | 0.231 |
| Operation time | 926 ± 201 min | 935 ± 161 min | 919 ± 226 min | 0.580 |
| Red blood cells | 19.9 ± 15.8 U | 17.2 ± 9.8 U | 21.9 ± 19.0 U | 0.014 |
| Platelet | 14.8 ± 9.1 U | 14.9 ± 7.4 U | 14.6 ± 10.3 U | 0.771 |
| Fresh‐frozen plasma | 25.8 ± 17.2 U | 24.4 ± 12.3 U | 26.9 ± 20.1 U | 0.761 |
| Cold ischemia | 77.9 ± 28.3 min | 78.0 ± 28.3 min | 77.4 ± 28.1 min | 0.673 |
| Warm ischemia | 45.0 ± 15.6 min | 44.9 ± 15.7 min | 45.5 ± 15.4 min | 0.382 |
HBV, hepatitis B virus; HCV, hepatitis C virus; AIH, autoimmune hepatitis; ACLF, acute‐on‐chronic liver failure; SBC, secondary biliary cirrhosis; PBC, primary biliary cirrhosis; MELD, Model for End‐Stage Liver Disease; INR, international normalized ratio; HEP, hepatic encephalopathy; HRS, hepatorenal syndrome; ICU, intensive care unit; HCC, hepatocellular carcinoma; GRWR, graft‐to‐recipient weight ratio; U, units; RL, right hemiliver; LL, left hemiliver; Dual, dual graft with two left livers or right and left liver