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editorial
. 2017 Feb 10;90(4):720–737. doi: 10.1111/tpj.13429

Figure 4.

Figure 4

Reconstruction process of mechanistic models of living organisms.

The model can be used to generate hypothesis on the function of a biological system and design experiments to validate this hypothesis. Hence, discovery may be accelerated thanks to focused experiments. The new knowledge obtained can be integrated in the model in an iterative process. In the toy model depicted activation of X by A (hypothesis A) or B (hypothesis B) in a given condition is investigated.