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. 2016 Oct 28;43(5):409–418. doi: 10.1111/nan.12363

Table 4.

Negative binomial regression analyses on the relationship between cardiovascular risk factors and microinfarcts

Risk factors IRR 95% CI (IRR) P IRR 95% CI (IRR) P IRR 95% CI (IRR) P
Cortical microinfarct Subcortical lesion Total microinfarct
Angina 1.53 (0.90; 2.60) 0.110 0.96 (0.47; 1.94) 0.910 1.35 (0.86; 2.13) 0.200
Stroke 2.74 (1.62; 4.64) <0.001 1.91 (1.02; 3.59) 0.040 2.47 (1.58; 3.87) <0.001
DM 0.75 (0.34; 1.63) 0.460 0.71 (0.25; 2.02) 0.520 0.72 (0.37; 1.40) 0.330
HTN 1.42 (0.89; 2.26) 0.140 1.56 (0.90; 2.69) 0.110 1.47 (1.00; 2.18) 0.050
MI 1.42 (0.75; 2.67) 0.280 1.01 (0.45; 2.29) 0.980 1.29 (0.75; 2.22) 0.360
ε4 0.57 (0.31; 1.05) 0.070 1.35 (0.68; 2.67) 0.400 0.78 (0.48; 1.27) 0.310
CAA 1.47 (0.89; 2.44) 0.130 1.25 (0.68; 2.29) 0.470 1.39 (0.90; 2.13) 0.130

DM, diabetes mellitus; HTN, systemic hypertension; MI, myocardial infarction; ε4, 1 or 2 Apolipoprotein E ε4 alleles; CAA, cerebral amyloid angiopathy.