Table 2.
Comparison of surgical strategies, pathological details and length of hospital stay
| Variables | All patients (n = 59) | Age <60 years (n = 31) | Age >70 years (n = 28) | p value |
|---|---|---|---|---|
| Resection | ||||
| Right hemihepatectomy | 17 (28.8) | 9 (29.0) | 8 (28.6) | 0.969 |
| Left hemihepatectomy | 2 (3.4) | 0 (0.0) | 2 (7.1) | 0.130 |
| Right extended hemihepatectomy | 25 (42.4) | 15 (48.4) | 10 (35.7) | 0.325 |
| Left extended hemihepatectomy | 2 (3.4) | 1 (3.2) | 1 (3.6) | – |
| Uni-segmentectomy or multi-metastasectomy | 6 (10.2) | 4 (12.9) | 2 (7.1) | 0.465 |
| Multi-segmentectomy | 7 (11.9) | 2 (6.5) | 5 (17.9) | 0.176 |
| Operative details | ||||
| Estimated blood loss, ml, median (range) | 1,000 (100–5,500) | 600 (100–5,500) | 1,350 (300–2,500) | 0.480 |
| Duration of operation, min, median (range) | 284 (113–510) | 315 (120–510) | 253 (113–444) | 0.012 |
| Percentage with Pringle maneuvre | 10.5 | 6.5 | 15.4 | 0.274 |
| ALPPS procedure | 6 (10.2) | 4 (12.9) | 2 (7.1) | 0.465 |
| Combined with PPPD | 2 (3.4) | 2 (6.5) | 0 (0.0) | – |
| Additional vascular or biliary procedure | 21 (35.6) | 16 (51.6) | 5 (17.9) | 0.007 |
| Postoperative laboratory details, median (range) | ||||
| INR on POD 5, ratio | 1.11 (0.94–1.45) | 1.13 (0.94–1.45) | 1.09 (1.00–1.38) | 0.599 |
| Bilirubin POD 5, mg/dl | 0.8 (0.4–5.1) | 0.8 (0.5–5.1) | 0.7 (0.4–3.7) | 0.134 |
| Peak bilirubin, mg/dl | 1.7 (0.5–23.1) | 1.8 (0.9–23.1) | 1.5 (0.5–10.2) | 0.060 |
| Pathology | ||||
| Percentage with R0 resections | 88.9 | 89.3 | 88.5 | 0.923 |
| Percentage with R1 resections | 11.1 | 10.7 | 11.5 | 0.923 |
| Length of hospital stay, days, median (range) | ||||
| Intensive care unit | 1 (0–38 | 1 (1–31) | 1 (0–38) | 0.585 |
| Postoperative nights | 15 (2–86) | 17 (2–86) | 12 (5–81) | 0.171 |
| LOS | 17 (6–112) | 18 (7–87) | 15 (6–112) | 0.174 |
| Readmissions | ||||
| Number of patients readmitted | 15 (25.4) | 11 (35.5) | 4 (14.3) | 0.062 |
| Postoperative nights including readmission, days, median (range) | 15 (5–90) | 19 (5–90) | 13 (5–81) | 0.106 |