Table 3.

Univariate Analysis of Predictors of the Composite Outcome (Death or Heart Transplantation) in Children with Familial Dilated Cardiomyopathy (FDCM) or Idiopathic DCM (IDCM).

Characteristics	n/%	Hazard Ratio (95% CI)	P Value
Type of dilated cardiomyopathy	870		0.15
Familial dilated cardiomyopathy	223	Reference
Idiopathic dilated cardiomyopathy	647	1.18 (0.94–1.49)
Age at diagnosis, years	870	1.03 (1.01–1.05)	< 0.001
Age ≥ 1 year at diagnosis	52.6% (458/870)	1.39 (1.14–1.70)	0.001
Male	50.6% (440/870)	1.12 (0.92–1.36)	0.28
Race/ethnicity	852		0.03
White	462	Reference
Black	181	1.15 (0.90–1.46)
Hispanic	147	0.71 (0.52–0.95)
Other	62	0.82 (0.53–1.25)
CHF present at diagnosis	74.6% (648/869)	3.18 (2.36–4.29)	< 0.001
Family history of sudden death	−10.5% (76/727)	1.01 (0.72–1.40)	0.98
Echocardiographic z-scores
LV end-diastolic dimension	699	1.14 (1.09–1.19)	< 0.001
LV end-systolic dimension	614	1.16 (1.10–1.21)	< 0.001
LV fractional shortening	713	0.91 (0.87–0.94)	< 0.001
LV end-diastolic posterior wall thickness	553	1.04 (0.99–1.09)	0.15
End-diastolic septal thickness	515	1.02 (0.95–1.09)	0.67
LV mass	545	1.09 (1.05–1.13)	< 0.001

CHF, congestive heart failure; CI, confidence interval; LV, left ventricular.