Figure 2.

The time to detect “significant deterioration” using the best global, pointwise, and cluster trend analyses, in a longitudinal cohort of participants with early or suspected glaucoma. The best global analysis criterion to give specificity 95% in series of five test–retest visual fields was “MD worsening with P < 0.101.” The best pointwise criterion was “≥9 locations worsening with P < 0.138.” The best cluster trend criterion was “≥3 clusters worsening with P < 0.117.” Top panel: No confirmation of detected deterioration is required. Middle panel: Deterioration had to be confirmed after the inclusion of two subsequent visual fields. Bottom panel: Deterioration had to be confirmed after the inclusion of four subsequent visual fields.