Table 2.

Comparison of model performance in predicting ADA Cognitive Score with and without mTBM features. The base set of features used were MRI information (305 features), Sex, Gender, Age, ApoE and baseline MMSE score. 7 Hippocampus feature maps were used: Mid Distance, 3 lambda values of the mTBM, magnitude of the Jacobian map and the first two eigenvalues of the Jacobian (See Table 1 and Figure 1 for more details)

	Without hippocampal features	With hippocampal features
nMSE	0.345 ± 0.075	0.249 ± 0.039
wR	0.828 ± 0.036	0.873 ± 0.022
M06 rMSE	5.259 ± 0.872	4.534 ± 0.883
M12 rMSE	5.653 ± 1.143	4.989 ± 1.134
M24 rMSE	5.532 ± 1.029	4.885 ± 1.094
M36 rMSE	4.777 ± 0.833	4.055 ± 1.024
M48 rMSE	4.367 ± 1.179	3.164 ± 1.091