Table 2. Brain areas with significantly different BOLD responses in the second level using an independent t-test design for the contrast turning>walking in the virtual reality task, showing the PD+FOG>PD−NF peak voxel statistics.
Brain area | x | y | z | # voxels | T-value | Z-value | P-value |
---|---|---|---|---|---|---|---|
L—SMA—Premotor | −21 | −7 | 64 | 59 | −4.17 | 3.54 | <0.001 |
L—Parietal superior | −30 | −46 | 58 | 57 | −3.91 | 3.37 | <0.001 |
L—Inferior frontal | −30 | 35 | 13 | 35 | 3.58 | 3.14 | <0.002 |
R—Inferior frontal | 36 | 20 | 25 | 20 | 4.04 | 3.46 | <0.001 |
Abbreviations: BOLD, blood oxygen level-dependent; L—SMA, left supplementary motor area; PD+FOG, Parkinson’s disease patients with freezing of gait; PD−NF, Parkinson’s disease patients without freezing of gait; R, right.
k>20, P<0.005, uncorrected with coordinates in MNI space.