Table 1. Patients’ baseline characteristics.
| Characteristic | Number of patients (%) | Mean±s.d. [range] |
|---|---|---|
| Age, years | 61.6±10.5 [45.0–83.0] | |
|
Sex | ||
| Female | 19 (61) | |
| Male | 12 (39) | |
|
Ethnicity | ||
| Japanese | 23 (74) | |
| Taiwanese | 4 (13) | |
| Korean | 4 (13) | |
| Duration of PD, years | 12.4±5.1 [2.9–29.2] | |
| Levodopa dose,a mg/day | 30 (97) | 1,011.7±629.7 |
| ‘Off’ time, hours/day | 29 (94) | 7.4±2.3 [3.0–11.6] |
| ‘On’ time without troublesome dyskinesia, hours/day | 29 (94) | 7.5±2.5 [1.0–11.8] |
| ‘On’ time with troublesome dyskinesia, hours/day | 29 (94) | 1.1±2.3 [0.0–9.2] |
| PDQ-39 summary index | 30 (97) | 35.5±13.8 [8–67] |
| UPDRS total score | 30 (97) | 27.7±15.5 [2–60] |
| UPDRS Part II score | 30 (97) | 9.4±6.6 [0–24] |
| UPDRS Part III score | 30 (97) | 16.5±9.7 [1–42] |
Abbreviations: PDQ, Parkinson’s Disease Questionnaire; UPDRS, Unified Parkinson’s Disease Rating Scale.
N=31 except as noted. Daily hours of ‘off’ time and ‘on’ time with/without troublesome dyskinesia were recorded in the PD Symptom Diary, normalized to a 16 h waking day and averaged for the 3 days before the visit. ‘On’ time without troublesome dyskinesia is the sum of ‘on’ time without dyskinesia and ‘on’ time with non-troublesome dyskinesia.
a
Last full daily levodopa dose of levodopa–carbidopa immediate release tablets before the NJ procedure.