Table 3.
Univariate and Multivariate analysis of the association between distance to the anal verge and pathologic complete response (pCR)
| Univariate Analysis | Proportion with pCR (n/N) | ||
|---|---|---|---|
| < 4 cm | 16/146 | 11.0% | |
| 4 - 6 cm | 52/218 | 23.9% | |
| 6 - 8 cm | 63/247 | 25.5% | P = 0.002 |
| 8 - 10 cm | 26/157 | 16.6% | |
| > 10 cm | 8/59 | 13.6% | |
|
| |||
| Multivariate Analysis* | Odds Ratio | 95%CI | P Value |
|
| |||
| < 4 cm | 1 | ref | |
| 4 - 6 cm | 2.54 | 1.36 - 4.75 | |
| 6 - 8 cm | 2.55 | 1.37 - 4.74 | P = 0.008 |
| 8 - 10 cm | 1.74 | 0.87 - 3.48 | |
| > 10 cm | 1.29 | 0.51 - 3.28 | |
*
Adjusted for Clinical Tumor Stage, Clinical Nodal Stage, Grade and Year of Surgery