Table 5.

Univariate and Multivariate analysis of the association between distance to the anal verger and a) Complete pathologic tumor response (ypT0) and b) Complete Pathologic Nodal Response (ypN0).

Univariate Analysis	Proportion with ypT0 (n/N)			Proportion with ypN0 (n/N)*
< 4 cm	18/146	12.3%		73/95	76.8%
4 - 6 cm	52/218	23.9%		130/166	78.3%
6 - 8 cm	70/247	28.3%	P = 0.001	145/192	75.5%	P = 0.71
8 - 10 cm	26/157	16.6%		86/118	72.9%
> 10 cm	8/59	13.6%		32/46	69.6%
Multivariate Analysis	Odds Ratio	95%CI	P Value	Odds Ratio	95%CI	P Value
	Complete Tumor Response (ypT0)**			Complete Nodal response (ypN0)***
< 4 cm	1	ref		1	ref
4 - 6 cm	2.27	1.24 - 4.18		1.03	0.56 - 1.92
6 - 8 cm	2.67	1.47 - 4.85	P = 0.004	0.88	0.48 - 1.60	P = 0.63
8 - 10 cm	1.55	0.79 - 3.05		0.81	0.43 - 1.55
> 10 cm	1.18	0.47 – 2.96		0.58	0.26 - 1.31

^*Patients with positive nodes on preoperative staging

^**Adjusted for clinical T stage, clinical N stage, grade, year of surgery

^***Included only node positive patients on preoperative imaging, adjusted for clinical T stage, year of surgery