Table 6.
Comparison of characteristics between patients with a pathologic complete response (pCR) and those treated with a complete clinical response non-operatively (NOM)
| pCR | NOM | ||
|---|---|---|---|
|
Distance to the Anal Verge
| |||
| <4 cm | 16/165, 9.7% | 5/35, 14.3% | P = 0.026 |
| 4 - 6 cm | 52/165, 31.5% | 19/35, 54.3% | |
| 6 - 8 cm | 63/165, 38.2% | 4/35, 11.4% | |
| 8 - 10 cm | 26/165, 15.7% | 5/35, 14.3% | |
| >10 cm | 8/165, 4.9% | 2/35, 5.7% | |
|
| |||
|
Grade
| |||
| Well Differentiated | 4/165, 2.4% | 1/35, 2.9% | P = 0.997 |
| Moderately Differentiated | 148/165, 89.7% | 31/35, 88.6% | |
| Poorly Differentiated | 9/165, 5.5% | 2/35, 5.7% | |
| Unknown | 4/165, 2.4% | 1/35, 2.9% | |
|
| |||
|
Clinical Tumor Stage
| |||
| cT1 | 1/165, 0.6% | 1/35, 2.9% | 0.179 |
| cT2 | 33/165, 20.0% | 3/35, 8.6% | |
| cT3 | 127/165, 77.0% | 31/35, 88.6% | |
| cT4 | 4/165, 2.4% | 0/35, 0.0% | |
|
| |||
|
Clinical N Stage
| |||
| cN0 | 36/165, 21.8% | 8/35, 22.9% | P = 0.893 |
| cN+ | 129/165, 78.2% | 27/35, 77.1% | |
|
| |||
|
Clinical Stage
| |||
| Stage II | 36/165, 21.8% | 9/35, 25.7% | 0.616 |
| Stage III | 129/165, 78.2% | 26/35, 74.3% | |