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. Author manuscript; available in PMC: 2017 Jul 19.
Published in final edited form as: Eur Respir J. 2009 Feb 5;34(1):103–110. doi: 10.1183/09031936.00120408

Figure 3.

Figure 3

Reduced leptin receptor expression in lung parenchyma of AKR/J mice exposed to 4 months of cigarette smoke (CS) or room air. Representative images of a minimum of three mice per condition. a) Decreased immunohistochemical staining of leptin receptor (brown) in alveolar walls of smoke-exposed mice using polyclonal antibody against ObR and avidin-biotin-peroxidase complex method. Arrowheads denote preserved leptin receptor staining of alveolar macrophages after CS exposure. Arrows show reduced airspace wall staining in smoke-exposed mice. b) Reduced leptin receptor expression is also evident in airway epithelial cells of smoke-exposed mice. RA: room air exposed; AW: airway lumen.