Table 2.

Hemodynamic variables

Variables	Groups	Baseline	24 h	48 h	72 h
Heart rate (bpm)	Control	92 [84–102]	101 [90–112]	105 [92–121]	94 [82–108]
	Levo	102 [80–110]	108 [90–116]	108 [82–118]	103 [81–112]
MAP (mm Hg)	Control	73 [62–86]	80 [68–91]	78 [67–85]	73 [60–87]
	Levo	74 [60–84]	77 [65–91]	77 [60–88]	81 [74–94]
CI (l/min/m2)	Control	3.5 [3.2–4.4]	4.1 [3.7–4.9]	4.2 [3.8–5.1]	4 [3.1–4.9]
	Levo	4 [3–4.6]	4.5 [3.6–5.2]	4.4 [3.8–5.4]	4.7 [3.9–5.2]
CVP (mm Hg)	Control	10.2 [9–11.1]	9.2 [8.1–11.3]	10.5 [9–12.2]	10 [8.9–12.1]
	Levo	9.5 [8.2–10.9]	10.3 [9–12.1]	12.1 [10–13.4]	11[10.3–12.4]
DO2I (ml/min/m2)	Control	452 [387–532]	539 [402–631]	623.9 [567–730]	538.8 [497–602]
	Levo	546 [497–646]	594 [477–652]	588 [497–629]	611 [507–694]
VO2I (mL/min/m2)	Control	143 [87–212]	156 [94–282]	161 [94–302]	149 [76–227]
	Levo	151 [71–231]	167 [80–272]	159 [77–287]	141 [81–294]
O2-ER (%)	Control	26 [20–34]	25 [20–32]	26 [21–35]	28 [21–37]
	Levo	24 [19–32]	27[22–33]	25 [19–38]	26 [18–36]
NE Dose (μg/kg/min)	Control	0.2 [0.1–0.7]	0.27 [0.1–0.6]	0.25 [0.1–0.8]	0.29 [0.08–0.9]
	Levo	0.3 [0.1–0.8]	0.34 [0.2–0.9]	0.31[0.18–1.1]	0.29 [0.1–1]
Glycemia (mmol/L)	Control	12 [11.1–12.8]	10.3 [9–11.8]	10.8 [9.1–12.9]	10.1 [9.2–11.8]
	Levo	10.7 [9.1–12.4]	11.8 [10.1–12.9]	10.4 [8.9–12.4]	9.7 [8.7–10.9]
Fluid input, mL/24 h	Control	1,010 [902–1,220]	898 [778–1,120]	895 [778–1,129]	890 [778–1,001]
	Levo	1,185 [1,078–1,328]	997 [842–1,200]	912 [808–1,190]	909 [838–1,124]

Data are presented as median [25th; 75th percentile]. No statistically significant differences were found in any of the investigated variables.

CI indicates cardiac index; CVP, central venous pressure; DO₂I, systemic oxygen delivery index; MAP, mean arterial pressure; NE, norepinephrine; O2-ER, oxygen extraction ratio; VO₂I, oxygen consumption index.