Figure 3.

Combination therapy of anti-PD-L1 and 5-FU in RCC subcutaneous mouse model. Mice were randomly allocated to different groups to accept different treatments: IgG, anti-PD-L1 Abs, 5-FU, and 5-FU and anti-PD-L1 Abs. (A) The survival curves indicated that the mice treated with 5-FU and anti-PD-L1 Abs had longer survival times compared to the mice receiving 5-FU or anti-PD-L1 Abs single treatment. (B) The tumor volume increase of mice receiving 5-FU and anti-PD-L1 combination treatment was the slowest among all the treatment groups.