Table 3.

Comparison between BFPSCs and SC-AdSCs.

	Source	SC-AdSCs	BFPSCs	Ref
Volume of harvested adipose tissue	Human	37 ml	0.8 ml	[12]
Number of cells isolated form adipose tissue	Human	1.15 × 105 (cells/ml)	1.1 × 105 (cells/ml)	[12]
	Human	513 × 103 (cells/gram) after 1 week of culture	253 × 103 (cells/gram) after 1 week of culture	[9]
Number of cells	Human	1.3 × 106 after 21 days, starting from 6 × 104 AdSCs	5.9 × 105 after 21 days, starting from 6 × 104 AdSCs	[12]
Doubling time (h)	Human	73.5	126.5	[12]
	Swine	82.9	72.5	[13]
Morphology and size	Human	Fibroblast-like shape	Slightly smaller and rounder compared with SC-AdSCs	[12]
	Human	Fibroblast-like shape	Fibroblast-like shape	[13]
	Swine	Spindle-shaped morphology after seeding and fibroblast-like morphology after 7 days of culture	Similar to SC-AdSCs	[9]
Clonogenicity expressed as the percentage of cells able to produce CFU-F from passages 1 to 4	Human	—	9.2%	[12]
	Human	10.1%	8.9%	[13]
Expression of specific MSC markers	Human	CD73+, CD90+, and CD105+; CD14−, CD31−, and CD34−	Similar to SC-AdSCs	[12]
	Swine	(i) CD146+CD29+ was observed in initial passaged BFPSCs, but not SC-AdSCs		[9]
		(ii) CD34 was much higher in BFPSCs than in SC-AdSCs
		(iii) CD105 was not observed in BFPSCs at first but increased by passaging the cells
Collagen level increase by osteodifferentiated cells after 14 days of culture	Human	137.5%	74.5%	[12]
	Swine	87%	254%	[13]
ALP activity increase by osteodifferentiated cells after 14 days of culture	Human	553%	419%	[12]
	Swine	126%	201%	[13]
Adipogenic differentiation capacity after 14 days of culture	Human	No difference	No difference	[12]
GAGs content increase in chondrogenic-differentiated porcine cells after 21 days	Swine	184%	149%	[13]

CFU: colony-forming units; MSCs: mesenchymal stem cells; SC-AdSC: subcutaneous adipose stem cell; ALP: alkaline phosphate; GAG: glycosaminoglycan.