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. 2017 Jul 13;9:377–384. doi: 10.2147/CLEP.S136565

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© 2017 Brenner and Chen. This work is published and licensed by Dove Medical Press Limited

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Sensitivity for detecting CRC and APCL ≥1 cm and specificity of FOB Gold (using the original cutoff) compared to Cologuard in the MSDT study (data derived from Imperiale et al),⁷ with and without age adjustment of FOB Gold results to age distribution of MSDT study population: FIT-O, FOB Gold using original cutoff, no age adjustment; FIT-A, FOB Gold using original cutoff, age adjusted.

Abbreviations: CRC, colorectal cancer; APCL, advanced precancerous lesion; MSDT, multitarget stool DNA test; FIT, fecal immunochemical test.