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. Author manuscript; available in PMC: 2018 Jun 8.
Published in final edited form as: J Med Chem. 2017 May 24;60(11):4626–4635. doi: 10.1021/acs.jmedchem.7b00020

Figure 1.

Figure 1

Structures of the non-selective CaCC inhibitor 1,28 and TMEM16A inhibitors 2,29, 30 3,31 4,32 and the new class of cycloalkylthiophene inhibitors (10aa) described herein.