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. 2017 Jul 13;12:5023–5038. doi: 10.2147/IJN.S139207

Figure 9.

Figure 9

Penetration ability and inhibitory effect toward MCF7 spheroids.

Notes: (A) The formation process of MCF7 tumor spheroids. (B) Inhibitory effect of Pt complex and Tf-NGO@Pt toward MCF7 spheroids. Magnification ×200. Values presented as mean ± SD of triplicate results. (C) Penetration ability of Tf-NGO@Pt to MCF7 tumor spheroids. The spheroids were treated with coumarin-6-labeled nanoparticles for 12 hours. Drug concentration was 60 mM.

Abbreviations: Tf, transferrin; NGO, nanographene oxide.